19 of Medvedev's 21 titles have been earned on hard courts
A revitalized the Russian player claimed his initial championship for 882 days with victory over Corentin Moutet in the competition final.
The athlete, a former top-ranked player, has experienced a difficult period, managing just one match at the major tournaments and suffering a difficult moment at the American major.
His unpredictability on the ATP Tour - and difficulties with his serve in specific - caused him falling of the world's top 10 and eventually parting ways with long-term trainer his previous coach.
Now training with Johansson and his other coach, he has consistently improved in the recent weeks - climaxing in a closely contested 7-5 4-6 6-3 win over Frenchman Moutet.
This marks Medvedev's initial trophy following the Rome competition and maiden on a hardcourt since that period of that year.
The win also indicates Medvedev has secured 21 victories at 21 distinct events.
"It's the first time I'm at a event with my both daughters simultaneously, so to win a championship is especially meaningful," commented world number 14 the champion.
"This title is in honour of my younger daughter Victoria, because the maiden victory I got when my first daughter my daughter was born was for her."
The tennis star, the past champion, had been defeated in his previous six finals, including in that event earlier this year.
His counter-punching strategy and frequent outbursts on the tennis court had caused some to wonder if his skill to compete at the highest level was over.
But the 29-year-old has altered his approach in recent weeks, striving to approach the net and play aggressively, backed up by an enhanced serve.
Medvedev fought back from a break down in the initial set against the tricky Frenchman, taking four of the concluding five games to take the lead.
Both players exchanged breaks in the second set before the challenger, attempting for his first ATP Tour championship, gained dominance to force a decider.
The opponent saved 4 early opportunities in a tight deciding set before the Russian won the break to fifteen to close out the victory.
Fittingly, the winner earned the title with a point at the net, with the Frenchman failing to control a volley after two hours and 38 minutes.